Education & Training
Medical School
New York Medical College
Graduate Institution
Residency
Pediatrics
- Oregon Health & Science University-OHSU GME
Fellowship
Neonatal-Perinatal Medicine
- Oregon Health & Science University
Boards
Insurances
MU Health Care participates with most major managed care organizations. To find out whether MU Health Care is a participating provider in your insurance plan or network, or for information on co-payments and deductibles, please contact your insurance carrier directly.
Academic Information
Research Profile
Rachna Mamidi, MD, is a board-certified pediatrician who practices neonatal and perinatal medicine and cares for babies with fetal abnormalities. Her research focuses on improving outcomes for premature infants through continuous physiologic monitoring and a better understanding of neonatal respiratory and oxygen physiology. Dr. Mamidi’s work has examined noninvasive respiratory support, oxygen management and intermittent hypoxemia in preterm infants, including research demonstrating that extended continuous positive airway pressure (CPAP) reduces intermittent hypoxemia in stable preterm infants.
At the University of Missouri School of Medicine, she is building a research program that leverages continuously collected physiologic data to identify early biomarkers of neonatal disease. Her current work examines longitudinal patterns of oxygenation and respiratory support and their relationships with important outcomes of prematurity, particularly retinopathy of prematurity (ROP) and bronchopulmonary dysplasia (BPD). The long-term goal of this work is to identify physiologic signatures that improve early risk prediction and enable more individualized care for premature infants.
This research is supported by multidisciplinary collaborations across the School of Medicine and University of Missouri, including neonatology, pediatric ophthalmology, clinical informatics, engineering, biostatistics and clinical research. Through these collaborations, Dr. Mamidi aims to develop innovative approaches that transform routinely collected neonatal monitoring data into clinically meaningful tools for predicting disease and improving outcomes for vulnerable infants.
Research Interests
- Retinopathy of prematurity (ROP)
- Bronchopulmonary dysplasia (BPD)
- Physiologic biomarkers of neonatal disease
- Prediction of outcomes in premature infants
- Individualized care and risk stratification in premature infants
Research Areas of Expertise
- Neonatal respiratory physiology
- Intermittent hypoxemia
- Oxygen management in preterm infants
- Noninvasive respiratory support and CPAP
- Continuous physiologic monitoring and longitudinal data analysis
- Clinical research in premature infants
Awards & Honors
- American Academy of Pediatrics, Section on Neonatal-Perinatal Medicine (2017–current)
- American Academy of Pediatrics, Missouri Chapter (2025–current)
- Cindy T. McEvoy Award for Outstanding Fellow Research, Oregon Health & Science University, Portland, OR (2024)
- Pratt Foundation Fellowship, Portland, OR (2022–2024)
- NHLBI Pulmonary T32 Research Fellowship, National Institutes of Health (2022–2024)
Publications
Rachna Mamidi, MD Bibliography
- Mamidi RR, Go MDA, Harris J, et al.
Extended Continuous Positive Airway Pressure in Infants Born Preterm Decreases Intermittent Hypoxemia: A Secondary Analysis of a Randomized Controlled Trial.
J Pediatr. 2026;296:115165. doi:10.1016/j.jpeds.2026..115165
Featured in: The Incubator’s Journal Club, Episode #447, “Does Extended CPAP Reduce Intermittent Hypoxemia in Stable Preterm Infants?”, June 10, 2026 - Mamidi RR, MacDonald KD, Spindel ER, McEvoy CT.
Interventions to Improve Lung Growth in Premature Infants. Paediatr Respir Rev.
Published online November 21, 2025 (ahead of print). doi:10.1016/j.prrv.2025.11.007 - Mamidi RR, McEvoy CT.
Extending CPAP in Stable Preterm Infants to Increase Lung Growth and Development as Measured by Pulmonary Function Testing.
Semin Perinatol. 2025;49(5):152059. doi:10.1016/j.semperi.2025.152059 - McEvoy CT, MacDonald KD, Go M, Milner K, Harris J, Schilling, D, Olson M, Tiller C, James SE, Bjerregarrd J, Vu A, Mamidi RR, Schelonka RL, Cynthia MD, Tepper RS.
Extended Continuous Positive Airway Pressure in Preterm Infants Increases Lung Growth at 6 Months: A Randomized Controlled Trial.
Am J Respir Crit Care Med. 2025;211(4):610-618. doi:10.1164/rccm.202411-2169OC - Mamidi RR, McEvoy CT.
Oxygen in the neonatal ICU: a complicated history and where are we now?
Front Pediatr. 2024;12:1371710. doi:10.3389/fped.2024.1371710 - Mamidi RR, MacDonald KD, Brumbach BH, Go MDA, McEvoy CT.
Nasal continuous positive airway pressure practices in preterm infants: A survey of neonatal providers.
J Neonatal-Perinat Med. 2023;16(4):611-617. doi:10.3233/NPM-230006 - Mamidi RR, Austin JP, Roberts C.
Recurrent Episodes of Hypotonia, Encephalopathy, and Quadriparesis in a 3-Year-Old Female.
Clin Pediatr (Phila). 2020;59(2):211-215. doi:10.1177/0009922819886872 - Zheng Z, Yin W, Zara JN, Li W, Kwak J, Mamidi RR, Lee M, Siu RK, Wang J, Carpenter D, Zhang X, Wu B, Ting K, Soo C.
The use of BMP-2 coupled – Nanosilver-PLGA composite grafts to induce bone repair in grossly infected segmental defects.
Biomaterials. 2010;31(35):9293-9300. doi:10.1016/j.biomaterials.2010.08.041